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Daphnoretin

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Chemical Structure| 2034-69-7 同义名 : Dephnoretin;Thymelol;Daphnoretin, NSC 291852, NSC291852, NSC-291852, BRN 1299325, BRN1299325, BRN-1299325;NSC 291852
CAS号 : 2034-69-7
货号 : A905085
分子式 : C19H12O7
纯度 : 98%
分子量 : 352.294
MDL号 : MFCD01082318
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 25 mg/mL(70.96 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Daphnoretin, a natural product isolated and purified from the roots of Wikstroemia indica (Linn.) C. A. Mey., has strong antiviral activity, mainly on the later phase of the replication cycle. Daphnoretin also has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through promoting apoptosis in a mitochondria-mediated way.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.84mL

0.57mL

0.28mL

14.19mL

2.84mL

1.42mL

28.39mL

5.68mL

2.84mL
参考文献

[1]Jiang HF, Wu Z, et al. Effect of daphnoretin on the proliferation and apoptosis of A549 lung cancer cells in vitro.. Oncol Lett. 2014 Sep;8(3):1139-1142.

[2]Yang ZY, Kan JT, et al. Daphnoretin-induced apoptosis in HeLa cells: a possible mitochondria-dependent pathway. Cytotechnology. 2014 Jan;66(1):51-61.