Cyclovirobuxine D

产品说明书

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Chemical Structure| 860-79-7 同义名 : 环维黄杨星D ;Cyclovirobuxin D;CVB-D;NSC 91722;Bebuxine;Cyclovirobuxine
CAS号 : 860-79-7
货号 : A897778
分子式 : C26H46N2O
纯度 : 98%
分子量 : 402.656
MDL号 : MFCD00468040
存储条件:

Pure form Keep in dark place,Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

无水乙醇: 12.5 mg/mL(31.04 mM),配合低频超声助溶,注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇

动物实验配方:
生物活性
描述 Cyclovirobuxine D is an active compound extracted from Buxus microphylla, which has been used for treating acute myocardial ischemia.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.48mL

0.50mL

0.25mL

12.42mL

2.48mL

1.24mL

24.84mL

4.97mL

2.48mL

参考文献

[1]Hu D, Liu X, et al. Cyclovirobuxine D ameliorates acute myocardial ischemia by K(ATP) channel opening, nitric oxide release and anti-thrombosis. Eur J Pharmacol. 2007 Aug 13;569(1-2):103-9.

[2]Grossini E, Battaglia A, et al. Coronary effects of cyclovirobuxine D in anesthetized pigs and in isolated porcine coronary arteries. Life Sci. 1999;65(5):PL59-65.