生物活性 | |||
---|---|---|---|
描述 | SAG is a highly effective agonist of the Smoothened (Smo) receptor (EC50=3 nM; Kd=59 nM). It activates the Hedgehog signaling pathway and antagonizes the inhibitory effects of Cyclopamine on Smo[1][2][3]. |
实验方案 | |||
---|---|---|---|
1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.04mL 0.41mL 0.20mL |
10.20mL 2.04mL 1.02mL |
20.41mL 4.08mL 2.04mL |
参考文献 |
---|