Chlormadinone acetate

产品说明书

Print
Chemical Structure| 302-22-7 同义名 : 醋酸氯地孕酮 ;NSC 92338; Gestafortin
CAS号 : 302-22-7
货号 : A876871
分子式 : C23H29ClO4
纯度 : 98%
分子量 : 404.93
MDL号 : MFCD00056471
存储条件:

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 9 mg/mL(22.23 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:

IP 2% DMSO+2% Tween80+30% PEG300+water 0.4 mg/mL clear

PO 0.5% CMC-Na 60 mg/mL suspension

生物活性
描述 Chlormadinone acetate is a steroidal progestin, with antiandrogen and antiestrogenic effects.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00842140 Polycystic Ovary Syndrome Not Applicable Completed - Brazil ... 展开 >> University of Sao Paulo Ribeirao Preto, Sao Paulo, Brazil, 14049-900 收起 <<
NCT01123538 Pharmacogenomics ... 展开 >> Systems Biology 收起 << Phase 4 Unknown October 2012 Norway ... 展开 >> Gynecology center, Helse Nord Bodø, Norway 收起 <<
NCT01608698 Body Weight Changes Phase 4 Unknown February 2016 Thailand ... 展开 >> Family Planning Unit, Department of Obstetric and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok, Thailand, 10700 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.47mL

0.49mL

0.25mL

12.35mL

2.47mL

1.23mL

24.70mL

4.94mL

2.47mL

参考文献

[1]Shibata Y, Fukabori Y, et al. Comparison of histological compositions and apoptosis in canine spontaneous benign prostatic hyperplasia treated with androgen suppressive agents chlormadinone acetate and finasteride. J Urol. 2001 Jan;165(1):289-93.