产品说明书

JPH203

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Chemical Structure| 1037592-40-7 同义名 : KYT-0353;Nanvuranlat;JPH-203SBECD
CAS号 : 1037592-40-7
货号 : A871573
分子式 : C23H19Cl2N3O4
纯度 : 99%+
分子量 : 472.321
MDL号 : MFCD30534398
存储条件：

粉末 Keep in dark place,Inert atmosphere,Room temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 JPH203 is a potent and selective L-type amino acid transporter 1 inhibitor (LAT1), used for cancer research.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.12mL

0.42mL

0.21mL

10.59mL

2.12mL

1.06mL

21.17mL

4.23mL

2.12mL
参考文献

[1]Choi DW, Kim DK, et al. JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells. Korean J Physiol Pharmacol. 2017 Nov;21(6):599-607.

[2]Yun DW, Lee SA, et al. JPH203, an L-type amino acid transporter 1-selective compound, induces apoptosis of YD-38 human oral cancer cells. J Pharmacol Sci. 2014;124(2):208-17.