产品说明书

N-Nornuciferine

Print
Chemical Structure| 4846-19-9 同义名 : Daechualkaloid E;Sanjoinine Ia;(–)-Nornuciferine;(R)-Nornuciferine
CAS号 : 4846-19-9
货号 : A861174
分子式 : C18H19NO2
纯度 : 98%
分子量 : 281.349
MDL号 : MFCD26406146
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(373.2 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 N-Nornuciferine, a natural product isolated and purified from the fruits of Piper nigrum, can competitively inhibit CYP2D6 activity with Ki values of 2.34 uM.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.55mL

0.71mL

0.36mL

17.77mL

3.55mL

1.78mL

35.54mL

7.11mL

3.55mL
参考文献

[1]Ye LH, He XX, et al. Identification and characterization of potent CYP2D6 inhibitors in lotus leaves. J Ethnopharmacol. 2014 Apr 11;153(1):190-6.

[2]Ma W, Lu Y, et al. Application of ionic liquids based microwave-assisted extraction of three alkaloids N-nornuciferine, O-nornuciferine, and nuciferine from lotus leaf. Talanta. 2010 Jan 15;80(3):1292-7.