产品说明书

Octadecanal

Print
Chemical Structure| 638-66-4 同义名 : 十八烷醛
CAS号 : 638-66-4
货号 : A860342
分子式 : C18H36O
纯度 : 98%
分子量 : 268.478
MDL号 : -
存储条件:

粉末 Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Octadecanal is a long-chain aldehyde and the principal free fatty aldehydes present[1]. Intact SLS (Sjögren-Larsson syndrome) fibroblasts oxidized octadecanol to fatty acid at less than 10% of the normal rate, but oxidized free octadecanal normally, suggesting that the FALDH (fatty aldehyde dehydrogenase) affected in SLS is chiefly involved in the oxidation of fatty alcohol to fatty acid[2]. With octadecanal, a burst phase of product formation, k(prod) = 3.4 ± 0.5 min(-1), is observed, indicating that chemistry is not rate-determining under the conditions of the assay[3].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.72mL

0.74mL

0.37mL

18.62mL

3.72mL

1.86mL

37.25mL

7.45mL

3.72mL

参考文献

[1]Gilbertson JR, Ferrell WJ, Gelman RA. Isolation and analysis of free fatty aldehydes from rat, dog, and bovine heart muscle. J Lipid Res. 1967 Jan;8(1):38-45

[2]Rizzo WB, Craft DA. Sjögren-Larsson syndrome. Deficient activity of the fatty aldehyde dehydrogenase component of fatty alcohol:NAD+ oxidoreductase in cultured fibroblasts. J Clin Invest. 1991 Nov;88(5):1643-8

[3]Eser BE, Das D, Han J, Jones PR, Marsh EN. Oxygen-independent alkane formation by non-heme iron-dependent cyanobacterial aldehyde decarbonylase: investigation of kinetics and requirement for an external electron donor. Biochemistry. 2011 Dec 13;50(49):10743-50