产品说明书

Procyanidin B1

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Chemical Structure| 20315-25-7 同义名 : (−)-Epicatechin-(4β-8)-(+)-catechin;Procyanidol B1;Epicatechin-(4beta->8)-ent-epicatechin;Proanthocyanidin B1
CAS号 : 20315-25-7
货号 : A843306
分子式 : C30H26O12
纯度 : 98%
分子量 : 578.52
MDL号 : MFCD01861512
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 25 mg/mL(43.21 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Procyanidin B1, a natrual product isolated and prufied from the fruits of Vitis vinifera L., inhibits infection by vesicular stomatitis virus and HCV pseudotype virus in Huh-7 cells, with IC50 of 29μM and 15μM, respectively.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.73mL

0.35mL

0.17mL

8.64mL

1.73mL

0.86mL

17.29mL

3.46mL

1.73mL
参考文献

[1]Terra X, Palozza P, et al. Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes. Free Radic Res. 2011 May;45(5):611-9.

[2]Xing J, Li R, et al. Anti-inflammatory effect of procyanidin B1 on LPS-treated THP1 cells via interaction with the TLR4-MD-2 heterodimer and p38 MAPK and NF-κB signaling. Mol Cell Biochem. 2015 Sep;407(1-2):89-95.