产品说明书

Deoxyelephantopin

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Chemical Structure| 29307-03-7 同义名 : -
CAS号 : 29307-03-7
货号 : A838524
分子式 : C19H20O6
纯度 : 98+%
分子量 : 344.36
MDL号 : MFCD01725517
存储条件：

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 35 mg/mL(101.64 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Deoxyelephantopin is a natural product isolated and purified from the herbs of Elephantopus scaber Linn. with hepatoprotective and antitumor activity, by inhibiting metastatic, inducing apoptosis, modulating oxidative stress , STAT3/p53/p21 signaling, MAPK pathway, PI3k/Akt/mTOR pathway, caspase cascades, and ROS .
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.90mL

0.58mL

0.29mL

14.52mL

2.90mL

1.45mL

29.04mL

5.81mL

2.90mL
参考文献

[1]Farha AK, Dhanya SR, et al. Deoxyelephantopin impairs growth of cervical carcinoma SiHa cells and induces apoptosis by targeting multiple molecular signaling pathways. Cell Biol Toxicol. 2014 Dec;30(6):331-43.

[2]Koe XF, Lim EL, et al. Evaluation of in vitro cytochrome P450 induction and inhibition activity of deoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber L. Food Chem Toxicol. 2013 Oct;60:98-108.