产品说明书
Ergosterol
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同义名 : | 麦角固醇 ;Ergosterin;Provitamin D;Ergosta-5,7,22-trien-3beta-ol;Provitamin D2 |
| CAS号 : | 57-87-4 | |
| 货号 : | A832534 | |
| 分子式 : | C28H44O | |
| 纯度 : | 95% | |
| 分子量 : | 396.648 | |
| MDL号 : | MFCD00003623 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 3 mg/mL(7.56 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO 无水乙醇: 2.5 mg/mL(6.3 mM)，配合低频超声，并水浴加热至45℃助溶，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇 |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Ergosterol is a membrane sterol, the specific molecule content was directly proportional to the mold size and species, over that linked to the different rates of biosynthesis among the diverse strains. The ergosterol amount in yeasts ranged from 1.37 × 101 to 7.63 × 102 pg/CFU[2].The strong interactions between the ergosterol and phospholipid molecules and the increase of the 2D domain condensation induced by the sterol presence should hamper the PLA2 activity. The level of ergosterol content in fungal membrane has crucial importance for its structure at the molecular scale[3]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT01843309 | Patients With Fungic Infection... 展开 >>s 收起 << | Phase 4 | Terminated(Not possible to com... 展开 >>plete the sample within the estimated time by the use of new antifungals) 收起 << | - | Mexico ... 展开 >> Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán México, Mexico, 14000 收起 << |
| NCT03563222 | Malnutrition, Child | Phase 4 | Not yet recruiting | November 2020 | - |
| NCT02057302 | Dyslipidemia | Phase 4 | Completed | - | - |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.52mL 0.50mL 0.25mL |
12.61mL 2.52mL 1.26mL |
25.21mL 5.04mL 2.52mL |
| 参考文献 |
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