产品说明书

Tetracaine HCl

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Chemical Structure| 136-47-0 同义名 : Amethocaine hydrochloride;Tetracaine hydrochloride;Niphanoid;Menonasal;Leocaine;Intercaine;PantocaineM;Gingicain;Decicain;Curtacain;Butylocaine
CAS号 : 136-47-0
货号 : A824667
分子式 : C15H25ClN2O2
纯度 : 98%
分子量 : 300.824
MDL号 : MFCD00038912
存储条件:

粉末 Inert atmosphere,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 30 mg/mL(99.73 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 50 mg/mL(166.21 mM),配合低频超声助溶

动物实验配方:
生物活性
靶点
  • Calcium Channel

描述 Tetracaine hydrochloride is a potent local anaesthetic and a channel function allosteric inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.32mL

0.66mL

0.33mL

16.62mL

3.32mL

1.66mL

33.24mL

6.65mL

3.32mL

参考文献

[1]Waldman N, Densie IK, et al. Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial. Acad Emerg Med. 2014 Apr;21(4):374-82.

[2]Gan X, Liu S, et al. Determination of tetracaine hydrochloride by fluorescence quenching method with some aromatic amino acids as probes. J Fluoresc. 2012 Jan;22(1):129-35.