产品说明书

Evodiamine

Print
Chemical Structure| 518-17-2 同义名 : d-Evodiamine;Isoevodiamine;SC-16015;Q-100579;(+)-Evodiamine
CAS号 : 518-17-2
货号 : A818858
分子式 : C19H17N3O
纯度 : 98%
分子量 : 303.358
MDL号 : MFCD06407824
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 9 mg/mL(29.67 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Evodiamine, a natural product isolated and purified from the fruits of Evodia rutaecarpa (Juss.) Benth. with anti-oxidation, anti-inflammatory and anti-cancer effects, is an apoptosis inducer via the AKT pathway and an inhibitor of cancer cells proliferation via inhibition of MTDH expression and activation of apoptosis.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.30mL

0.66mL

0.33mL

16.48mL

3.30mL

1.65mL

32.96mL

6.59mL

3.30mL
参考文献

[1]Sachita K, Kim Y, et al. In Vitro Assessment of the Anticancer Potential of Evodiamine in Human Oral Cancer Cell Lines. Phytother Res. 2015 Aug;29(8):1145-51.

[2]Zou Y, Qin X, et al. Apoptosis of human non-small-cell lung cancer A549 cells triggered by evodiamine through MTDH-dependent signaling pathway. Tumour Biol. 2015 Jul;36(7):5187-93.