产品说明书

Acotiamide

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Chemical Structure| 185106-16-5 同义名 : YM443 free base;Z-338 free base;Z388;Acofide
CAS号 : 185106-16-5
货号 : A818654
分子式 : C21H30N4O5S
纯度 : 99%+
分子量 : 450.552
MDL号 : MFCD00953661
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Acotiamide is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. It acts as an acetylcholinesterase inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.22mL

0.44mL

0.22mL

11.10mL

2.22mL

1.11mL

22.19mL

4.44mL

2.22mL
参考文献

[1]Zai H, Matsueda K, et al. Effect of acotiamide on gastric emptying in healthy adult humans. Eur J Clin Invest. 2014 Dec;44(12):1215-21.

[2]Mayanagi S, Kishino M, et al. Efficacy of acotiamide in combination with esomeprazole for functional dyspepsia refractory to proton-pump inhibitor monotherapy. Tohoku J Exp Med. 2014;234(3):237-40.