产品说明书
Oxazolone
 |
同义名 : | - |
| CAS号 : | 15646-46-5 | |
| 货号 : | A818543 | |
| 分子式 : | C12H11NO3 | |
| 纯度 : | 95% | |
| 分子量 : | 217.221 | |
| MDL号 : | MFCD00003204 | |
| 存储条件： |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(483.38 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Oxazolone acts as a haptenizing agent that triggers acute or chronic inflammation in the large intestine, making it suitable for developing colitis models. It leads to Th1/Th2-dependent colitis characterized by weight loss and diarrhea. The inflammation caused by oxazolone can be alleviated with neutralizing antibodies against IL-4 or TNF-α or with decoy IL-13R2-α-FC proteins[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
4.60mL 0.92mL 0.46mL |
23.02mL 4.60mL 2.30mL |
46.04mL 9.21mL 4.60mL |
| 参考文献 |
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