产品说明书

Edoxudine

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Chemical Structure| 15176-29-1 同义名 : 依度尿苷 ;EUDR
CAS号 : 15176-29-1
货号 : A803144
分子式 : C11H16N2O5
纯度 : 95%
分子量 : 256.255
MDL号 : MFCD00079191
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(468.28 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 50 mg/mL(195.12 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Edoxudine, an analog of thymidine, is an antiviral drug shows effectiveness against herpes simplex virus.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.90mL

0.78mL

0.39mL

19.51mL

3.90mL

1.95mL

39.02mL

7.80mL

3.90mL
参考文献

[1]Kulikowski T. Structure-activity relationships and conformational features of antiherpetic pyrimidine and purine nucleoside analogues. A review. Pharm World Sci. 1994 Apr 15;16(2):127-38.

[2]Sacks SL, Tyrrell LD, et al. Randomized, double-blind, placebo-controlled, clinic-initiated, Canadian multicenter trial of topical edoxudine 3.0% cream in the treatment of recurrent genital herpes. Canadian Cooperative Study Group. J Infect Dis. 1991 Oct;164(4):665-72.