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peimisine

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Chemical Structure| 19773-24-1 同义名 : Ebeiensine
CAS号 : 19773-24-1
货号 : A802034
分子式 : C27H41NO3
纯度 : 98%
分子量 : 427.619
MDL号 : MFCD30207851
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 12 mg/mL(28.06 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Peimisine (Ebeiensine) acts as an antagonist of muscarinic M receptors and an inhibitor of angiotensin-converting enzyme (ACE). It exhibits antitumor, anti-inflammatory, and antihypertensive activities. Additionally, peimisine is known to induce apoptosis and is utilized in research related to cough and asthma[1][2][3].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.34mL

0.47mL

0.23mL

11.69mL

2.34mL

1.17mL

23.39mL

4.68mL

2.34mL
参考文献

[1]Pan F, et al. Peimisine and peiminine production by endophytic fungus Fusarium sp. isolated from Fritillaria unibracteata var. wabensis. Phytomedicine. 2014 Jul-Aug;21(8-9):1104-9.

[2]Armando Alberola-Die, et al. Peimine, an Anti-Inflammatory Compound from Chinese Herbal Extracts, Modulates Muscle-Type Nicotinic Receptors. Int J Mol Sci. 2021 Oct 19;22(20):11287.

[3]Dongdong Wang, et al. Evaluation of antitumor property of extracts and steroidal alkaloids from the cultivated Bulbus Fritillariae ussuriensis and preliminary investigation of its mechanism of action. BMC Complement Altern Med. 2015 Feb 21;15:29.