Dimercaprol

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Chemical Structure| 59-52-9 同义名 : 2,3-二巯基丙-1-醇 ;Dithioglycerol;2,3-Dimercapto-1-propanol;HSDB4004
CAS号 : 59-52-9
货号 : A794824
分子式 : C3H8OS2
纯度 : 99%
分子量 : 124.225
MDL号 : MFCD00004864
存储条件：

Pure form Keep in dark place,Inert atmosphere,Room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 40 mg/mL(322 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 (2,3-Dimercapto-1-propanol) acts as an anti-heavy metal-poisoning agent and also demonstrates anti-HIV properties. It is used in research related to the poisoning by metals such as arsenic, mercury, gold, lead, antimony, and more[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

8.05mL

1.61mL

0.80mL

40.25mL

8.05mL

4.02mL

80.50mL

16.10mL

8.05mL
参考文献

[1]Kubota S, et al. 2,3 Dimercapto-1-propanol inhibits HIV-1 tat activity, viral production, and infectivity in vitro. AIDS Res Hum Retroviruses. 1990 Jul;6(7):919-27.

[2]Ran Tian, et al. Dimercaprol is an acrolein scavenger that mitigates acrolein-mediated PC-12 cells toxicity and reduces acrolein in rat following spinal cord injury. J Neurochem. 2017 Jun;141(5):708-720.

[3]Taciane Roza, et al. 2,3-Dimercapto-1-propanol does not alter the porphobilinogen synthase inhibition but decreases the mercury content in liver and kidney of suckling rats exposed to HgCl2. Basic Clin Pharmacol Toxicol. 2005 Apr;96(4):302-8.