产品说明书

Mesaconitine

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Chemical Structure| 2752-64-9 同义名 : 新乌头碱;新乌碱;美沙乌头碱
CAS号 : 2752-64-9
货号 : A788219
分子式 : C33H45NO11
纯度 : 98%
分子量 : 631.711
MDL号 : MFCD00210528
存储条件:

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

无水乙醇: 4 mg/mL(6.33 mM),配合低频超声助溶,注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇

动物实验配方:
生物活性
靶点
  • Calcium Channel

描述 Mesaconitine is the main active component of genus aconitum plants.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.58mL

0.32mL

0.16mL

7.92mL

1.58mL

0.79mL

15.83mL

3.17mL

1.58mL

参考文献

[1]Ogura J, Mitamura M, et al. Mesaconitine-induced relaxation in rat aorta: role of Na+/Ca2+ exchangers in endothelial cells. Eur J Pharmacol. 2004 Jan 12;483(2-3):139-46.

[2]Mitamura M, Horie S, et al. Mesaconitine-induced relaxation in rat aorta: involvement of Ca2+ influx and nitric-oxide synthase in the endothelium. Eur J Pharmacol. 2002 Feb 2;436(3):217-25.