产品说明书

Furomollugin

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Chemical Structure| 61658-41-1 同义名 : -
CAS号 : 61658-41-1
货号 : A780094
分子式 : C14H10O4
纯度 : 98+%
分子量 : 242.23
MDL号 : -
存储条件：

粉末

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Furomollugin is a natural product isolated and purified from the roots of Rubia cordifolia L. with antiviral activity, can strongly suppress the secretion of hepatitis B surface antigen (HBsAg), with IC50 of 2.0 mg/mL, in human hepatoma Hep3B cells.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.13mL

0.83mL

0.41mL

20.64mL

4.13mL

2.06mL

41.28mL

8.26mL

4.13mL
参考文献

[1]Kraus GA, Dong P. Phthalide Anions in Organic Synthesis. A Direct Total Synthesis of Furomollugin. Nat Prod Commun. 2015 Jun;10(6):1025-6.

[2]Xia L, Lee YR. A novel and efficient synthesis of diverse dihydronaphtho[1,2-b] furans using the ceric ammonium nitrate-catalyzed formal [3 + 2] cycloaddition of 1,4-naphthoquinones to olefins and its application to furomollugin. Org Biomol Chem. 2013 Sep 28;11(36):6097-107.