产品说明书

Eperezolid

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Chemical Structure| 165800-04-4 同义名 : PNU-100592
CAS号 : 165800-04-4
货号 : A772637
分子式 : C18H23FN4O5
纯度 : 99%+
分子量 : 394.397
MDL号 : MFCD00941980
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 45 mg/mL(114.1 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Eperezolid is an oxazolidinone antibacterial agent, demonstrating good in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci (MIC90 = 1-4 mg/mL).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.54mL

0.51mL

0.25mL

12.68mL

2.54mL

1.27mL

25.36mL

5.07mL

2.54mL
参考文献

[1]Zhou CC, Swaney SM, et al. 1H nuclear magnetic resonance study of oxazolidinone binding to bacterial ribosomes. Antimicrob Agents Chemother. 2002 Mar;46(3):625-9.

[2]Lin AH, Murray RW, et al. The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. Antimicrob Agents Chemother. 1997 Oct;41(10):2127-31.