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Procyanidin B2

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Chemical Structure| 29106-49-8 同义名 : Proanthocyanidin B2;(−)-Epicatechin-(4β→8)-(−)-epicatechin;Procyanidol B2;PCB2
CAS号 : 29106-49-8
货号 : A772396
分子式 : C30H26O12
纯度 : 99%+
分子量 : 578.52
MDL号 : MFCD01861513
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(86.43 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 65 mg/mL(112.36 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Procyanidin B2 exerts a potent and beneficial role in reducing granulosa cell apoptosis and inducing autophagy process,and exerts a variety of potent protective pharmacological effects on diabetic complications.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT03214276 Healthy Not Applicable Completed - -
NCT03194620 Healthy Not Applicable Completed - United States, California ... 展开 >> UC Davis Davis, California, United States, 95616 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.73mL

0.35mL

0.17mL

8.64mL

1.73mL

0.86mL

17.29mL

3.46mL

1.73mL
参考文献

[1]Zhang JQ, Gao BW, et al. Critical Role of FoxO1 in Granulosa Cell Apoptosis Caused by Oxidative Stress and Protective Effects of Grape Seed Procyanidin B2. Oxid Med Cell Longev. 2016;2016:6147345.

[2]Zhou Y, Li BY, et al. Restoration of Mimecan Expression by Grape Seed Procyanidin B2 Through Regulation of Nuclear Factor-kappaB in Mice With Diabetic Nephropathy. Iran J Kidney Dis. 2016 Sep;10(5):325-331.