Resorantel

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Chemical Structure| 20788-07-2 同义名 : -
CAS号 : 20788-07-2
货号 : A767963
分子式 : C13H10BrNO3
纯度 : 97%
分子量 : 308.127
MDL号 : MFCD00864511
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(811.35 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Resorentel is a safe anti antiparasitic drug. Resorantel at a dosage rate of 130 mg *kg-1 live body mass was found to be highly effective against Houttuynia struthionis in ostriches when dosed alone or in combination with fenbendazole or levamisole[1]. The anthelmintic efficacy of resorantel against Thysaniezia giardi and Avitellina spp. was tested in sheep at a dosage rate of 65 mg kg-1 live mass. The reduction obtained was 100% in at least 80% of the treated flock[2]. A 2- tertiary-butyl benzthiazole compound (CGA 72630) at 25 mg/kg and resorantel at 65 mg/kg had very high efficacy against both adult and immature fluke in the rumen and small intestine respectively[3]. While fenbendazole at 15 mg kg-1 either alone or in combination with resorantel reduced the total burden of Libyostrongylus douglassi by more than 98%, levamisole alone at 30 mg kg-1 was only 28% effective, and in combination with resorantel its efficacy was 67%[4].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.25mL

0.65mL

0.32mL

16.23mL

3.25mL

1.62mL

32.45mL

6.49mL

3.25mL
参考文献

[1]Gruss B, Malan FS, Roper NA, du Plessis C, Ashburner AJ. The anthelmintic efficacy of resorantel against Houttuynia struthionis in ostriches. J S Afr Vet Assoc. 1988;59(4):207‐208

[2]Gruss B, Malan FS, Roper NA, du Plessis CA, Ashburner AJ. The anthelmintic efficacy of resorantel against cestodes in sheep. J S Afr Vet Assoc. 1988;59(4):204‐205

[3]Rolfe PF, Boray JC. Chemotherapy of paramphistomosis in sheep. Aust Vet J. 1988;65(5):148‐150

[4]Malan FS, Gruss B, Roper NA, Ashburner AJ, du Plessis CA. Resistance of Libyostrongylus douglassi in ostriches to levamisole. J S Afr Vet Assoc. 1988;59(4):202‐203