产品说明书

1-Docosanol

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Chemical Structure| 661-19-8 同义名 : 1-二十二醇;二十二醇;二十二烷醇 ;Behenyl alcohol;n-Docosanol;Nacol-22-97;Abreva;NAA-422;NSC 8407;Docosyl Alcohol;Docosanol
CAS号 : 661-19-8
货号 : A762512
分子式 : C22H46O
纯度 : 95% mixture of isomers
分子量 : 326.6
MDL号 : MFCD00002939
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

无水乙醇: 50 mg/mL(153.09 mM)，配合低频超声助溶，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇
动物实验配方：
生物活性
描述 1-Docosanol (Behenyl alcohol) is a saturated fatty alcohol with activity against lipid-enveloped viruses, including herpes simplex virus (HSV)[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.06mL

0.61mL

0.31mL

15.31mL

3.06mL

1.53mL

30.62mL

6.12mL

3.06mL
参考文献

[1]Katz DH, et al. Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex. Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10825-9.

[2]Sacks SL, et al. Clinical efficacy of topical docosanol 10% cream for herpes simplex labialis: A multicenter, randomized, placebo-controlled trial. J Am Acad Dermatol. 2001 Aug;45(2):222-30.

[3]Iglesias G, et al. The toxicity of behenyl alcohol. I. Genotoxicity and subchronic toxicity in rats and dogs. Regul Toxicol Pharmacol. 2002 Aug;36(1):69-79.