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Aminooxy-PEG4-alcohol

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Chemical Structure| 106492-60-8 同义名 : -
CAS号 : 106492-60-8
货号 : A761994
分子式 : C8H19NO5
纯度 : 95%
分子量 : 209.24
MDL号 : MFCD30828691
存储条件:

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Aminooxy-PEG4-alcohol serves as a non-cleavable 4-unit PEG ADC linker employed in the production of antibody-drug conjugates (ADCs) [1]. Aminooxy-PEG4-alcohol also functions as a PEG-based PROTAC linker applicable in PROTAC synthesis [2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.78mL

0.96mL

0.48mL

23.90mL

4.78mL

2.39mL

47.79mL

9.56mL

4.78mL

参考文献

[1]Heather D. Maynard, et al. Method of creating hydrogels through oxime bond formation. US20150202305A1.

[2]Murray BS, et al. Reactive thermoresponsive copolymer scaffolds. Chem Commun (Camb). 2010 Dec 7;46(45):8651-3.