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Des(benzylpyridyl) Atazanavir

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Chemical Structure| 1192224-24-0 同义名 : Atazanavir metabolite M1
CAS号 : 1192224-24-0
货号 : A761523
分子式 : C26H43N5O7
纯度 : 95%
分子量 : 537.649
MDL号 : MFCD28023587
存储条件：

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Des(benzylpyridyl) Atazanavir is an N-dealkylation metabolite of Atazanavir, emerges from the biotransformation process of Atazanavir, a potent inhibitor specifically targeting the HIV-1 protease. This metabolite might play a role in both the therapeutic effects and adverse interactions associated with Atazanavir, serving as a focus for further investigation into the drug's impact[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.86mL

0.37mL

0.19mL

9.30mL

1.86mL

0.93mL

18.60mL

3.72mL

1.86mL
参考文献

[1]R ter Heine, et al. Identification and profiling of circulating metabolites of atazanavir, a HIV protease inhibitor. Drug Metab Dispos. 2009 Sep;37(9):1826-40.