Castanospermine

产品说明书

Print
Chemical Structure| 79831-76-8 同义名 : 栗精胺 ;6,7-Diepicastanospermine;NSC 625381;1,6,7,8-Tetrahydroxyoctahydroindolizine;6-Epicastanospermine
CAS号 : 79831-76-8
货号 : A758766
分子式 : C8H15NO4
纯度 : 98%+
分子量 : 189.209
MDL号 : MFCD00017555
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(554.94 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(528.52 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Castanospermine inhibits all forms of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.29mL

1.06mL

0.53mL

26.43mL

5.29mL

2.64mL

52.85mL

10.57mL

5.29mL
参考文献

[1]Gruters RA, Neefjes JJ, et al. Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase. Nature. 1987 Nov 5-11;330(6143):74-7.

[2]Saul R, Molyneux RJ, et al. Studies on the mechanism of castanospermine inhibition of alpha- and beta-glucosidases. Arch Biochem Biophys. 1984 May 1;230(2):668-75.