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Scutebarbatine A

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Chemical Structure| 176520-13-1 同义名 : (-)-Scutebarbatine A
CAS号 : 176520-13-1
货号 : A757677
分子式 : C32H34N2O7
纯度 : 99+%
分子量 : 558.622
MDL号 : MFCD17214881
存储条件：

粉末 2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Scutebarbatine A, a natural product isolated and purified from the herbs of Scutellaria barbata D. Don, shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspase-3 and 9, and down-regulating Bcl-2, and a significant ability to protect cells against H2O2 with ED50 values of 5.0 and 16.8 uM, respectively.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.79mL

0.36mL

0.18mL

8.95mL

1.79mL

0.90mL

17.90mL

3.58mL

1.79mL
参考文献

[1]Yang XK, Xu MY, et al. In vitro and in vivo antitumor activity of scutebarbatine A on human lung carcinoma A549 cell lines. Molecules. 2014 Jun 25;19(7):8740-51.