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Corosolic acid

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Chemical Structure| 4547-24-4 同义名 : Colosolic acid;Glucosol;2α-Hydroxyursolic acid;Colosic acid
CAS号 : 4547-24-4
货号 : A746827
分子式 : C30H48O4
纯度 : 99%
分子量 : 472.7
MDL号 : MFCD06794973
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 25 mg/mL(52.89 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Corosolic acid is a natural product isolated and purified from the barks of Lagerstroemia speciosa with anti-angiogenic and anti-lymphangiogenic effects on in vitro endothelial cells.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT03388762 Prediabetic State Not Applicable Recruiting September 2019 United States, Maryland ... 展开 >> University of Maryland Center for Diabetes and Endocrinology Recruiting Baltimore, Maryland, United States, 21201 Contact: Kashif Munir, MD    443-682-6800    kmunir@medicine.umaryland.edu    University of Maryland Family Medicine Associates Recruiting Baltimore, Maryland, United States, 21201 Contact: Mary Bahr-Robertson    410-706-6155    mbahr@som.umaryland.edu    University of Maryland School of Medicine, Department of Family and Community Medicine, East Hall Not yet recruiting Baltimore, Maryland, United States, 21201 Contact: Mary Bahr-Robertson    410-706-6155    mbahr@som.umaryland.edu    United States, Ohio Alliance Integrative Medicine Recruiting Cincinnati, Ohio, United States, 45236 Contact: Lisa Gallagher, ND    513-791-5521    lisa.gallagher@myhealingpartner.com 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.12mL

0.42mL

0.21mL

10.58mL

2.12mL

1.06mL

21.16mL

4.23mL

2.12mL
参考文献

[1]Yoo KH, Park JH, et al. Corosolic Acid Exhibits Anti-angiogenic and Anti-lymphangiogenic Effects on In Vitro Endothelial Cells and on an In Vivo CT-26 Colon Carcinoma Animal Model. Phytother Res. 2015 May;29(5):714-23.

[2]Ahn KS, Hahm MS, et al. Corosolic acid isolated from the fruit of Crataegus pinnatifida var. psilosa is a protein kinase C inhibitor as well as a cytotoxic agent. Planta Med. 1998 Jun;64(5):468-70.