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Karanjin

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Chemical Structure| 521-88-0 同义名 : 干华豆晶 4
CAS号 : 521-88-0
货号 : A743358
分子式 : C18H12O4
纯度 : 98%
分子量 : 292.286
MDL号 : MFCD00017406
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 35 mg/mL(119.75 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Karanjin, a natural product isolated and purified from the seeds of the karanja tree (Millettia pinnata or Pongamia glabra Vent.), has an effects on cell cycle arrest and apoptosis in human A549, HepG2 and HL-60 cancer cells.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.42mL

0.68mL

0.34mL

17.11mL

3.42mL

1.71mL

34.21mL

6.84mL

3.42mL
参考文献

[1]Yi D, Wang Z, Yi L. Development and validation of an LC-MS method for determination of Karanjin in rat plasma: application to preclinical pharmacokinetics. J Chromatogr Sci. 2015 Apr;53(4):456-61.

[2]Guo JR, Chen QQ, et al. Effects of karanjin on cell cycle arrest and apoptosis in human A549, HepG2 and HL-60 cancer cells. Biol Res. 2015 Jul 26;48:40.