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(Z)-10-Hydroxynortriptyline

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Chemical Structure| 47132-19-4 同义名 : cis-10-hydroxy Nortriptyline;10(Z)-hydroxy Nortriptyline
CAS号 : 47132-19-4
货号 : A736895
分子式 : C19H21NO
纯度 : 99%
分子量 : 279.376
MDL号 : -
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 (Z)-10-Hydroxynortriptyline, a derivative of Nortriptyline, acts as a secondary product of its metabolism. Nortriptyline itself is a tricyclic antidepressant, primarily derived from Amitriptyline, and serves to alleviate depressive symptoms[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.58mL

0.72mL

0.36mL

17.90mL

3.58mL

1.79mL

35.79mL

7.16mL

3.58mL
参考文献

[1]Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.