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Esculentoside A

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Chemical Structure| 65497-07-6 同义名 : -
CAS号 : 65497-07-6
货号 : A736780
分子式 : C42H66O16
纯度 : 98%
分子量 : 826.96
MDL号 : MFCD27980582
存储条件：

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(126.97 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Esculentoside A, a natural product isolated and purified from the roots of Phytolacca acinosa Roxb with anti-infalmmatory activity, may be useful for the treatment of autoimmune disease through modulation on T cell-mediated adaptive immunity, play significant roles in the treatment of BXSB mice through modulation of inflammatory cytokines, inhibition of renal cell proliferation and induction of apoptosis, and suppress inflammatory responses in LPS-induced ALI through inhibition of the nuclear factor kappa B and mitogen activated protein kinase signaling pathways.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.21mL

0.24mL

0.12mL

6.05mL

1.21mL

0.60mL

12.09mL

2.42mL

1.21mL
参考文献

[1]Zhang F, Wang X, et al. The protective effect of Esculentoside A on experimental acute liver injury in mice. PLoS One. 2014 Nov 18;9(11):e113107.

[2]Zhong WT, Jiang LX, et al. Protective effect of esculentoside A on lipopolysaccharide-induced acute lung injury in mice. J Surg Res. 2013 Nov;185(1):364-72.