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m-3M3FBS

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Chemical Structure| 200933-14-8 同义名 : -
CAS号 : 200933-14-8
货号 : A732625
分子式 : C16H16F3NO2S
纯度 : 99%+
分子量 : 343.364
MDL号 : MFCD00095824
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(305.8 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 m-3M3FBS acts as a potent activator of phospholipase C (PLC), enhancing superoxide production in human neutrophils, increasing intracellular calcium levels, and promoting inositol phosphate generation across various cell lines, leading to apoptosis in monocytic leukemia cells[1].[2].[3].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.91mL

0.58mL

0.29mL

14.56mL

2.91mL

1.46mL

29.12mL

5.82mL

2.91mL
参考文献

[1]Bae YS, et al. Identification of a compound that directly stimulates phospholipase C activity. Mol Pharmacol. 2003;63(5):1043-1050.

[2]Krjukova J, et al. Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation. Br J Pharmacol. 2004;143(1):3-7.

[3]Lee YN, et al. The novel phospholipase C activator, m-3M3FBS, induces monocytic leukemia cell apoptosis. Cancer Lett. 2005;222(2):227-235.