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Bruceantin

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Chemical Structure| 41451-75-6 同义名 : 鸦胆停 ;NCI165563;NSC165563;(–)-Bruceantin;(-)-Bruceantin
CAS号 : 41451-75-6
货号 : A730084
分子式 : C28H36O11
纯度 : 98+%
分子量 : 548.579
MDL号 : MFCD00866510
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(191.4 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Bruceantin is first isolated from Brucea antidysenterica, a tree used in Ethiopia for the treatment of cancer, and activity was observed against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.82mL

0.36mL

0.18mL

9.11mL

1.82mL

0.91mL

18.23mL

3.65mL

1.82mL
参考文献

[1]Cuendet M, Christov K, et al. Multiple myeloma regression mediated by bruceantin. Clin Cancer Res. 2004 Feb 1;10(3):1170-9.

[2]Cuendet M, Pezzuto JM. Antitumor activity of bruceantin: an old drug with new promise. J Nat Prod. 2004 Feb;67(2):269-72.