产品说明书
Dexelvucitabine
 |
同义名 : | Reverset;d-d4FC;DOC-817. trade name: Reverset.;YZ-817;PSI-5582;INCB-8721;RVT;DPC-817;DFC;beta-D-D-4FC |
| CAS号 : | 134379-77-4 | |
| 货号 : | A728211 | |
| 分子式 : | C9H10FN3O3 | |
| 纯度 : | 98% | |
| 分子量 : | 227.192 | |
| MDL号 : | MFCD09954118 | |
| 存储条件： |
粉末 Keep in dark place,Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 50 mg/mL(220.08 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Dexelvucitabine is a nucleoside reverse transcriptase inhibitor potentially for the treatment of HIV infection. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT00040157 | HIV Infections | Phase 2 | Terminated(Safety concerns) | - | United States, Arizona ... 展开 >> Body Positive, Inc. Phoenix, Arizona, United States, 85006 United States, California L.a., California, United States Pacific Horizon Medical Group, Inc. San Francisco, California, United States, 94115 United States, Florida Community Health Care Center One, Inc. Ft. Lauderdale, Florida, United States, 33306 South Shore Hospital Miami Beach, Florida, United States, 33160 United States, Georgia AIDS Research Consortium Atlanta, Georgia, United States, 30308 United States, Illinois Chicago, Illinois, United States United States, New York St. Lukes Roosevelt Hospital New York, New York, United States, 10019 Stony Brook University Infectious Disease, Dept. of Medicine Stony Brook, New York, United States, 11794-8153 United States, Texas Houston, Texas, United States, 77098 Houston, Texas, United States United States, Virginia Hampton Road Medical Specialists Hampton, Virginia, United States, 23666 United States, Washington Swedish Medical Center Seattle, Washington, United States, 98122 收起 << |
| NCT00037622 | Chronic Hepatitis B | Not Applicable | Terminated(Safety concerns fro... 展开 >>m other studies.) 收起 << | - | - |
| NCT00034359 | Hepatitis B, Chronic | Phase 2 | Completed | - | Bulgaria ... 展开 >> Clinic of Gastroenterology Sofia, Bulgaria Foundation of Gastroenterology Sofia, Bulgaria Former Yugoslavia Clinic Center of Serbia, Institute of Infectious Disease Belgrade, Former Yugoslavia Clinic of Novi Sad Novi Sad, Former Yugoslavia 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
4.40mL 0.88mL 0.44mL |
22.01mL 4.40mL 2.20mL |
44.02mL 8.80mL 4.40mL |
| 参考文献 |
|---|
|
[1]Meusinger R. Doubling spectroscopy challenge. Anal Bioanal Chem. 2015 Nov;407(27):8169-72. |