产品说明书

Ficusin A

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Chemical Structure| 173429-83-9 同义名 : -
CAS号 : 173429-83-9
货号 : A720488
分子式 : C25H24O5
纯度 : 98+%
分子量 : 404.455
MDL号 : -
存储条件:

粉末

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Ficusin A is a natural product isolated and purified from the seeds of Psoralea corylifolia Linn. with antioxidant, antilipidemic and antidiabetic effects. It can lower the levels of fasting blood glucose, plasma insulin, body weight gain in HFD-STZ induced diabetic rats, and can significantly enhance the PPARγ expression and improve the translocation and activation of GLUT4 in the adipose tissue, suggests that ficusin improves the insulin sensitivity on adipose tissue and it can be used for the treatment of obesity related type 2 diabetes mellitusl.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.47mL

0.49mL

0.25mL

12.36mL

2.47mL

1.24mL

24.72mL

4.94mL

2.47mL

参考文献

[1]Irudayaraj SS, Stalin A, et al. Antioxidant, antilipidemic and antidiabetic effects of ficusin with their effects on GLUT4 translocation and PPARγ expression in type 2 diabetic rats. Chem Biol Interact. 2016 Aug 25;256:85-93.