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Excisanin A

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Chemical Structure| 78536-37-5 同义名 : -
CAS号 : 78536-37-5
货号 : A707712
分子式 : C20H30O5
纯度 : 99+%
分子量 : 350.449
MDL号 : -
存储条件:

粉末

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Excisanin A, a diterpenoid compound isolated and purified from Isodon macrocalyxin D, inhibits the invasive behavior of breast cancer cells by modulating the integrin β1/FAK/PI3K/AKT/β-catenin signaling.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.85mL

0.57mL

0.29mL

14.27mL

2.85mL

1.43mL

28.53mL

5.71mL

2.85mL

参考文献

[1]Qin J, Tang J, et al. A diterpenoid compound, excisanin A, inhibits the invasive behavior of breast cancer cells by modulating the integrin β1/FAK/PI3K/AKT/β-catenin signaling. Life Sci. 2013 Nov 4;93(18-19):655-63.

[2]Aoyagi Y, Nishioka Y, et al. Synthesis of 1-O-monoacyl or 12-O-monoacyl, 1-,12-O-diacyl-, and 11,12-dehydrated excisanin A 7,14-acetonides and their cytotoxic activity. Bioorg Med Chem. 2006 Sep 1;14(17):5802-11.