产品说明书

SR 49059

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Chemical Structure| 150375-75-0 同义名 : Relcovaptan
CAS号 : 150375-75-0
货号 : A706003
分子式 : C28H27Cl2N3O7S
纯度 : 99%+
分子量 : 620.501
MDL号 : MFCD00922133
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(169.22 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 SR 49059 is a potent, orally active, and selective antagonist of the vasopressin V1a receptor, with a Ki value of 1.4 nM[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.61mL

0.32mL

0.16mL

8.06mL

1.61mL

0.81mL

16.12mL

3.22mL

1.61mL

参考文献

[1]Serradeil-Le Gal C, et al. Effect of SR-49059, a vasopressin V1a antagonist, on human vascular smooth muscle cells. Am J Physiol. 1995 Jan;268(1 Pt 2):H404-10.

[2]Shuaib A, et al. Effects of nonpeptide V(1) vasopressin receptor antagonist SR-49059 on infarction volume and recovery of function in a focal embolic stroke model. Stroke. 2002 Dec;33(12):3033-7.