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Reverse T3

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Chemical Structure| 5817-39-0 同义名 : 3,3’,5’-T3;rT3;HLN 17390;Reverse triiodothyronine;3,3',5'-Triiodothyronine;3,3',5'-Triiodo-L-thyronine;3′,5′,3-Triiodothyronine
CAS号 : 5817-39-0
货号 : A702834
分子式 : C15H12I3NO4
纯度 : 98%
分子量 : 650.973
MDL号 : MFCD00036864
存储条件：

粉末 Keep in dark place,Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 4 mg/mL(6.14 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 3 mg/mL(4.61 mM)，配合低频超声，并水浴加热至45℃助溶
动物实验配方：
生物活性
描述 Reverse triiodothyronine is an isomer of triiodothyronine(3,5,3'-triiodothyronine, T3).
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT03634176 - Completed - Venezuela ... 展开 >> Hospital Dr Miguel Perez Carreño Caracas, Venezuela, Bolivarian Republic Of, Venezuela, 1020 收起 <<
NCT01182285 Thyroid Neoplasm Phase 2 Completed - United States, Maryland ... 展开 >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 收起 <<
NCT01182285 - Completed - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.54mL

0.31mL

0.15mL

7.68mL

1.54mL

0.77mL

15.36mL

3.07mL

1.54mL
参考文献

[1]Jakowczuk M, Zalas D, et al. Permanent atrial fibrillation in heart failure patients as another condition with increased reverse triiodothyronine concentration. Neuro Endocrinol Lett. 2016 Sep;37(4):337-342.

[2]Horacek J, Dusilova Sulkova S, et al. Thyroid hormone abnormalities in hemodialyzed patients: low triiodothyronine as well as high reverse triiodothyronine are associated with increased mortality. Physiol Res. 2012;61(5):495-501.