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Naringenin triacetate

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Chemical Structure| 3682-04-0 同义名 : -
CAS号 : 3682-04-0
货号 : A699967
分子式 : C21H18O8
纯度 : 98%
分子量 : 398.363
MDL号 : N/A
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(263.58 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Naringenin triacetate is a natural product isolated and purified from the fruits of Citrus aurantium L. with a better binding affinity with multiple crystal structures of first bromodomain BRD4 (BRD4 BD1) when compared with the known inhibitors.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.51mL

0.50mL

0.25mL

12.55mL

2.51mL

1.26mL

25.10mL

5.02mL

2.51mL
参考文献

[1]Yamashita Y, Hanaya K, et al. Simple Synthesis of Sakuranetin and Selinone via a Common Intermediate, Utilizing Complementary Regioselectivity in the Deacetylation of Naringenin Triacetate. Chem Pharm Bull (Tokyo). 2016;64(7):961-5.