产品说明书

Palonosetron

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Chemical Structure| 135729-61-2 同义名 : RS25259;RS 25259 197
CAS号 : 135729-61-2
货号 : A692800
分子式 : C19H24N2O
纯度 : 98+%
分子量 : 296.407
MDL号 : MFCD07783848
存储条件：

粉末

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
靶点

  • 5-HT3
描述 Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.37mL

0.67mL

0.34mL

16.87mL

3.37mL

1.69mL

33.74mL

6.75mL

3.37mL
参考文献

[1]Blazer M, Phillips G, et al. Antiemetic control with palonosetron in patients with gastrointestinal cancer receiving a fluoropyrimidine-based regimen in addition to either irinotecan or oxaliplatin: a retrospective study. Oncology. 2012;83(3):135-40.

[2]Celio L, Agustoni F, et al. Palonosetron: an evidence-based choice in prevention of nausea and vomiting induced by moderately emetogenic chemotherapy. Tumori. 2012 May-Jun;98(3):279-86.