Laninamivir

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Chemical Structure| 203120-17-6 同义名 : R 125489
CAS号 : 203120-17-6
货号 : A688887
分子式 : C13H22N4O7
纯度 : 99%+
分子量 : 346.336
MDL号 : MFCD18071611
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 5 mg/mL(14.44 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Laninamivir (R 125489) exhibits potent inhibition of influenza neuraminidase (NA), demonstrating IC50 values of 0.90 nM, 1.83 nM, and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1), and A/RI/5+/1957 H2N2 N2 (p57N2), respectively [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.89mL

0.58mL

0.29mL

14.44mL

2.89mL

1.44mL

28.87mL

5.77mL

2.89mL
参考文献

[1]Vavricka CJ, et al. Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition. PLoS Pathog. 2011 Oct;7(10):e1002249.