产品说明书

Dabigatran (ethyl ester)

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Chemical Structure| 429658-95-7 同义名 : -
CAS号 : 429658-95-7
货号 : A686750
分子式 : C27H29N7O3
纯度 : 97%
分子量 : 499.564
MDL号 : MFCD16294325
存储条件:

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.00mL

0.40mL

0.20mL

10.01mL

2.00mL

1.00mL

20.02mL

4.00mL

2.00mL

参考文献

[1]Preetpal SS,Aiye L, et al. Rational Design of Potent, Small, Synthetic Allosteric Inhibitors of Thrombin. J Med Chem. 2011; 54(15): 5522-5531.

[2]Santiago R, Maria-Paz M, et al. Pharmacological basis and clinical evidence of dabigatran therapy. J Hematol Oncol. 2011; 4: 53.