产品说明书

Demethylwedelolactone

Print
Chemical Structure| 6468-55-9 同义名 : 异去甲蟛蜞菊内酯 ;DWL;1,3,8,9-Tetrahydroxycoumestan;Norwedelolactone
CAS号 : 6468-55-9
货号 : A672934
分子式 : C15H8O7
纯度 : 98+%
分子量 : 300.22
MDL号 : MFCD09264645
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(349.74 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Demethylwedelolactone, a natural product isolated and purified from the herbs of Eclipta prostrata, has trypsin inhibitory effect. Demethylwedelolactone exerts anti-invasive growth effect on breast cancer cells.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.33mL

0.67mL

0.33mL

16.65mL

3.33mL

1.67mL

33.31mL

6.66mL

3.33mL
参考文献

[1]Lee YJ, Lin WL, et al. Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. Eur J Med Chem. 2012 Oct;56:361-7.

[2]Syed SD, Deepak M, et al. Trypsin inhibitory effect of wedelolactone and demethylwedelolactone. Phytother Res. 2003 Apr;17(4):420-1.