Cytochalasin B

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Chemical Structure| 14930-96-2 同义名 : Phomin;NSC 107658
CAS号 : 14930-96-2
货号 : A671790
分子式 : C29H37NO5
纯度 : 98%
分子量 : 479.61
MDL号 : MFCD00077704
存储条件:

Pure form Sealed in dry,Store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 85 mg/mL(177.23 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

无水乙醇: 25 mg/mL(52.13 mM),配合低频超声助溶,注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇

动物实验配方:
生物活性
描述 Cytochalasin B, a metabolite of the fungus Drechslera dematoidea, is an cell-permeable inhibitor of actin polymerization which inhibits cell division, migration and glucose transport and causes G2/M cell cycle arrest and apoptosis in HCT-116 colorectal carcinoma cells.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT03663634 Infertility Not Applicable Recruiting August 1, 2019 Egypt ... 展开 >> IbnSina IVF Center Recruiting Sohag, Egypt Contact: Mohamed Fawzy, IVF Lab Director    +201011122286    drfawzy001@me.com 收起 <<
NCT03678558 Infertility Not Applicable Recruiting January 15, 2019 Egypt ... 展开 >> IbnSina IVF Center, IbnSina Hospital Recruiting Sohag, Egypt, 12345 Contact: Mohamed Fawzy, Lab Director    +201116604600    drfawzy001@me.com    Contact: Mohamed Y. Abdel-Rahman, M.D.    +201142456788    dryahyaz@yahoo.com    Principal Investigator: Mohamed Fawzy, Lab Director 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.09mL

0.42mL

0.21mL

10.43mL

2.09mL

1.04mL

20.85mL

4.17mL

2.09mL

参考文献

[1]Buldak RJ, Skonieczna M, et al. Changes in subcellular localization of visfatin in human colorectal HCT-116 carcinoma cell line after cytochalasin B treatment. Eur J Histochem. 2014 Sep 12;58(3):2408.

[2]Whitesell RR, Ardehali H, et al. Compartmentalization of transport and phosphorylation of glucose in a hepatoma cell line. Biochem J. 2005 Mar 1;386(Pt 2):245-53.