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Vasicinone

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Chemical Structure| 486-64-6 同义名 : (-)-Vasicinone
CAS号 : 486-64-6
货号 : A670398
分子式 : C11H10N2O2
纯度 : 98+%
分子量 : 202.21
MDL号 : MFCD06656332
存储条件：

粉末 2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(247.27 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Vasicinone, a natural product isolated and purified from the herb of Peganum harmala L., may act as a hepatoprotective agent, which has significant antitussive, expectorant, and bronchodilating activities and exhibits antiproliferative activity against human gastric cancer cells MCG-803.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.95mL

0.99mL

0.49mL

24.73mL

4.95mL

2.47mL

49.45mL

9.89mL

4.95mL
参考文献

[1]Liu W, Wang Y, et al. Antitussive, expectorant, and bronchodilating effects of quinazoline alkaloids (±)-vasicine, deoxyvasicine, and (±)-vasicinone from aerial parts of Peganum harmala L. Phytomedicine. 2015 Nov 15;22(12):1088-95.

[2]Sarkar C, Bose S, Banerjee S. Evaluation of hepatoprotective activity of vasicinone in mice. Indian J Exp Biol. 2014 Jul;52(7):705-11.