产品说明书
Clonixin
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同义名 : | SCH-10304;CBA 93626;Deltar;lysine clonixinate;NSC 335505;Clonixic acid |
| CAS号 : | 17737-65-4 | |
| 货号 : | A668370 | |
| 分子式 : | C13H11ClN2O2 | |
| 纯度 : | 98% | |
| 分子量 : | 262.692 | |
| MDL号 : | MFCD00864292 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,Room temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(399.71 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Clonixin is an orally active analgesic and a non-steroidal anti-inflammatory agent in rodents[2]. Clonixin increased membrane fluidity in a concentration dependent manner, with the highest perturbation occurring nearby the 2-AS probe, closely located to the bilayer surface[3]. In addition, a single oral dose of clonixin results in comparable blood levels in male patients suffering from rheumatoid arthritis and in healthy control subjects[4]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
3.81mL 0.76mL 0.38mL |
19.03mL 3.81mL 1.90mL |
38.07mL 7.61mL 3.81mL |
| 参考文献 |
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