产品说明书

Glucoraphanin

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Chemical Structure| 21414-41-5 同义名 : -
CAS号 : 21414-41-5
货号 : A666511
分子式 : C12H23NO10S3
纯度 : 99%+
分子量 : 437.507
MDL号 : MFCD08460269
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

H2O: 75 mg/mL(171.43 mM)

动物实验配方:
生物活性
描述 Glucoraphanin, a natural product isolated and purified from the seeds of Raphanus sativus L., with antioxidant and chemoprevention activiy, and can ameliorates obesity and insulin resistance through adipose tissue browning and reduction of metabolic endotoxemia in mice.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT03013465 Healthy Volunteers Not Applicable Completed - United States, Maryland ... 展开 >> USDA-ARS, Beltsville Human Nutrition Research Center Beltsville, Maryland, United States, 20705 收起 <<
NCT02821728 Prostate Cancer Not Applicable Completed - United Kingdom ... 展开 >> Institute of Food Research Norwich, Norfolk, United Kingdom, NR4 7UA 收起 <<
NCT02656420 Environmental Carcinogenesis Phase 1 Phase 2 Completed - China, Jiangsu ... 展开 >> Qidong Liver Cancer Institute Qidong, Jiangsu, China, 226200 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.29mL

0.46mL

0.23mL

11.43mL

2.29mL

1.14mL

22.86mL

4.57mL

2.29mL

参考文献

[1]Nagata N, Xu L, et al. Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice. Diabetes. 2017 May;66(5):1222-1236.

[2]Liu X, Wang Y, et al. Dietary Broccoli Alters Rat Cecal Microbiota to Improve Glucoraphanin Hydrolysis to Bioactive Isothiocyanates. Nutrients. 2017 Mar 10;9(3). pii: E262.