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靶点 |
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描述 | Ki16198 is a potent and orally active antagonist of LPA receptors, functioning as the methyl ester derivative of Ki16425. It demonstrates efficacy in inhibiting LPA1 and LPA3-induced inositol phosphate production, with Ki values of 0.34 μM and 0.93 μM, respectively, showcasing its potential against pancreatic cancer tumorigenesis and metastasis when applied in vivo[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.05mL 0.41mL 0.20mL |
10.23mL 2.05mL 1.02mL |
20.45mL 4.09mL 2.05mL |
参考文献 |
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