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Syringic acid

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Chemical Structure| 530-57-4 同义名 : 3,5-dimethyl ether Gallic Acid;NSC 2129;3,5-dimethoxy-4-hydroxy Benzoic Acid
CAS号 : 530-57-4
货号 : A663784
分子式 : C9H10O5
纯度 : 96%
分子量 : 198.17
MDL号 : MFCD00002552
存储条件：

粉末 Inert atmosphere,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 60 mg/mL(302.77 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Syringic acid, a natural product isolated and purified from the herbs of Michelia spaerantha C.Y.Wu, is an antimitogenic and chemo-sensitizing agent for human colorectal cancer, reduces oxidative stress and neuronal degeneration in treatment of cerebral ischemia and pretreatment of spinal cord ischemia/reperfusion, and exerts its chemotherapeutic and chemo-sensitizing effects through an array of mechanisms including cell-cycle arrest, apoptosis induction, inhibition of cell proliferation, cell migration, angiogenesis, NFκB DNA-binding and proteasome activities.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.05mL

1.01mL

0.50mL

25.23mL

5.05mL

2.52mL

50.46mL

10.09mL

5.05mL
参考文献

[1]Guven M, Aras AB, et al. The protective effect of syringic acid on ischemia injury in rat brain. Turk J Med Sci. 2015;45(1):233-40.

[2]Gargouri OD, Gargouri B, et al. Synthesis of 3-O-methylgallic acid a powerful antioxidant by electrochemical conversion of syringic acid. Biochim Biophys Acta. 2013 Jun;1830(6):3643-9.