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Euptox A

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Chemical Structure| 79491-71-7 同义名 : 9-Oxo-10,11-dehydroageraphorone
CAS号 : 79491-71-7
货号 : A660599
分子式 : C15H20O2
纯度 : 98+%
分子量 : 232.318
MDL号 : MFCD20260866
存储条件：

粉末

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 9-Oxo-10,11-dehydroageraphorone, a natural product isolated and purified from the herbs of Eupatorium adenophorum with acaricidal activity, induces hepatotoxicity and cholestasis in rats, effectively inhibits the proliferation of HeLa cells by arresting the cell cycle transition from S to G2/M phase, did not continue to complete the cell cycle activity and induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.30mL

0.86mL

0.43mL

21.52mL

4.30mL

2.15mL

43.04mL

8.61mL

4.30mL
参考文献

[1]Liao F, Hu Y, et al. Acaricidal activity of 9-oxo-10,11-dehydroageraphorone extracted from Eupatorium adenophorum in vitro. Exp Parasitol. 2014 May;140:8-11.

[2]Hu Y, Liao F, et al. Clinical efficacy of 9-oxo-10, 11-dehydroageraphorone extracted from Eupatorium adenophorum against Psoroptes cuniculi in rabbits. BMC Vet Res. 2014 Dec 20;10:970.